A claim that a prescription drug 'cures' rosacea and the manner Dave Fleming does it you can bet on a controversy. Dave can be credited with shouting this 'cure' to the world through yahoo groups in a manner that is wanting. All you have to do is read his yahoo group posts and find out why. I think my web site is one of the few places on the internet you can get any information on this subject other than Dave's yahoo group. Dave has been emailing me since I tried this prescription drug from the end of April 2004 for 141 days. You would think I had popped a cork from the flack I received trying this. However, I think I am a reasonable person and thought it worth the effort. My conclusion is written in a dairy for all to read. You can judge for yourself. But the fact remains that whenever a history is written on this subject of using this prescription drug for rosacea, Dave Fleming will no doubt be mentioned, and I will only get, I hope, an honorable mention for trying it.
Dave's yahoo group is at this url >
http://health.groups.yahoo.com/group/rosacea-cure/
Dave has some directions on using this prescription which I have made available by clicking here.
Dave is also very clear that this prescription is for TOPICAL DMSO 1 % Diflucan and not for ORAL Diflucan which you can read by clicking here for message 192 and clicking here for message 193. These directions were public but are now a private members only group which you have to join.
Dave has been banned from posting by two yahoo groups shortly after he reported his findings on their boards, in May 2003. These groups have never offered any public explanation of why this ban has remained or why all discussion of FLUCONAZOLE 1% SOLUTION has been barred from posting. No doubt the bans may have been imposed due to Dave's unusual manner of posting and for his rather zealous approach on the subject but it does seem odd that discussion on the subject is taboo in these groups especially since this is a prescription drug administered by compounding pharmacists. At any rate there are few yahoo groups that even allow posts on this subject. Other than the reports that are published at Dave Fleming's yahoo group there are few reported users outside his group.
The way Dave operates his yahoo group is unusual since he removes most of the email addresses and names of the posters and edits just about every post giving alias names for the users! The content of the posters is claimed by Dave to be not edited and is placed under his statement, however, my private emails to Dave have been posted at his yahoo group and edited which to me is not cool. In explaining this, Dave has stated repeatedly that he has been under constant 'cyber-attack' since May 2003, and he does not want the same to happen to his group members. Dave claims that there are powerful interests who want to stop or delay any new effective treatment for rosacea, because they are making so much money from rosaceans. Although that may be possible, given the amount of money spent by rosaceans every year, it is impossible for now to substantiate these 'cyber attacks.' Dave does point out that it is noteworthy that this prescription has been barred from being posted at least two yahoo groups even though the prescription can be obtained legally from a physician and CP.
Dave Fleming is a member of the rosaceans yahoo group and is restricted to use only 25 words about his thoughts on (FLUCONAZOLE 1% SOLUTION) and to give a url address where his longer post may be read at his group site. This restriction was arbitrarily imposed by the group owner to prevent some rosaceans members from being upset by Dave's long posts. A poll that was held on this subject brought only 19 votes out of the 400+ rosaceans members. This poll is listed in the POLLS section as a closed poll at the rosaceans group at yahoo. Dave has agreed to the restriction and posts all his detailed comments at his own yahoo group. Another poll was conducted later that allowed Dave to post freely again. However, when Dave is rude his posts are deleted. If you want examples of his rude comments all you have to do is go to his yahoo group and read the posts. The moderators of the rosaceans yahoo group have the freedom to delete any post they feel is in violation of the rules of the group. Dave's post that are allowed to remain are still public. Dave hasn't made any posts for several months at the rosaceans yahoo group.
While Dave may be credited with shouting this treatment out to the world that this is a 'cure' for rosacea, this controversy in the minds of most rosaceans is added to all the other false 'cure' claims for rosacea which have disappointed rosaceans in the past. Therefore, controversy has naturally surrounded Dave's claim and his unorthodox approach. One of the biggest differences between this 'cure' and all the other 'cures' for rosacea is this is a PRESCRIPTION, requiring a physician and a compounding pharmicist. All the other 'cures' are non-prescription.
There has been a number of emails sent to me about Dave Fleming's DMSO 1% Diflucan treatment for rosacea. Many are obviously concerned with the possible side effects or health ramifications of using a new prescription drug for rosacea without the clinical trials or studies that are usually required for new drugs. However, you should remember that in the USA a prescription from a physician is required to obtain this drug from a compounding pharmacist. The doctor and usually the compounding pharmacist monitors the administration and use of this drug. This is legal in the USA and not unethical. Most of us probably have not ever heard of compounding pharmacists. For information on compounding pharmacists click here. You may locate a CP by using the IACPRX referral service. For those of you who live in other countries please read my legal disclaimer. For your information I have published the following emails so that you can be fully aware of what some of these issues might be that have come to my attention.
On Friday, August 8, 2003, at 10:50 AM, akbreshears <abreshears@hotmail.com> wrote:
Re: DMSO Dangers
Hi Brady,
I wanted to copy this message to you about Dave's DMSO-fluconazole.
I know this has been discussed in this group in the past, but I
wasn't here then...I'm not sure what was said.
I thought I would leave it to your discretion if this needs to be
posted here. If this is old news or you just don't want it brought
up again, please just ignore it...
Thanks,
Angela
______________________________________________________________________
Posted to yahoo group: Rosacea-Cure
Hi Dave,
It's been a while since I've posted, so to refresh your memory (and
anyone else reading this); I last posted on message 131... Also, I
believe you asked me if I was on the payroll of the big drug
companies. I'm not sure if I responded, so I'll start with that. I
am a health care scientist, but NO...I am not on the payroll of any
drug company and will not profit from any statements I make. I
evaluate the profiles of orphan drugs to ensure the safety of
children in research (mostly cancer).
With that said I want to ask you again about your claim that this is
a completely benign treatment... And I am going to stand by my
belief that you cannot SAFELY say this without research. As you
know, the DMSO-fluconazole combination has not been evaluated in
controlled clinical trials (if you feel this is wrong-please let me
know), so I ran a literature search on DMSO which is the base you are
using. Here is some of what I found:
DMSO = Dimethyl Sulfoxide
Medical uses: Dimethyl sulfoxide has many applications in medicine.
Therapeutically, it is used as a topical anti-inflammatory. It is
also used in veterinary medicine; in plant pathology and nutrition;
and for the DIFFUSION OF DRUGS, ETC, INTO THE BLOODSTREAM BY TOPICAL
APPLICATION.
Kinetics: Dermal Absorption:
1) DMSO is absorbed systemically (tissues and body fluids) following
topical application.
2) Within 5 minutes of dermal application, DMSO can be detected in
the blood. Within 20 minutes it is throughout soft tissues, within
an hour it is found in bones and teeth.
Cautions: Approximately every 6 months, patients receiving DMSO
should have a biochemical screening, particularly liver and renal
function tests and complete blood count. DMSO has been reported to
cause eosinophilia when used topically. Topical DMSO has caused
sedation, neuropathy, headache, and dizziness.
DMSO can cause the liberation of histamine. There have been
occasional hypersensitivity reactions following topical
administration.
If the skin is not clear and dry, water will catalytically react to
produce heat.
Dave,
I could go on (both positive and negative) but I don't want to shut
down everyone's in-box! I just want every one to realize that if
they test this product they are at certain risk. If nothing else
they need to know about the water reaction. Burns have been reported
due to this. And DMSO can lead to liver damage (even before the
added risk of fluconazole!) if it is not monitored. One last thing
and I'll go...please look up Stevens-Johnson Syndrome. It is a rare
effect of fluconazole treatment. Yes it is very rare, but it is
possible and in severe cases may lead to death. Dave- I will
separately send you the additional info I have. If anyone else would
like a copy- feel free to contact me privately.
Angela
From: "akbreshears" <abreshears@h...>
Date: Fri Jun 20, 2003 9:39 am
Subject: Re: [rosaceans] Integrity, in Medical Care?
Message # 131
Dave,
I have to tell you that I am extremely disturbed by some things you
are saying. Your claims that this is completely harmless is at the
very least misleading. Just because this was harmless to you means
nothing to the next person who tries it. You have no idea what kind
of allergic reactions or permenant scars this could lead to in other
people! This has only been tested for nail fungus. Nails are very
different from the sensitive tissue on our faces!
Now I'm not trying to discount your claim that this worked for you
and I'm sure that you have nothing but the best intentions with this,
but if anyone is going to try this they should know that they are
putting themselves at risk. Then, if they are willing to take that
risk- Go for it! I'm considering trying this if my doctor will write
for it, but it will be in a very small area long before I would ever
use it in an obvious area.
Also, do you know what the term "off-label use" means? If not you
should look into that. What you are asking for is "off-label use"
not "controlled-trial use" as you've said before. These are two very
different things! Controlled-trials are full of additional safety
precautions and lab work to watch exactly how the drug is being
absorbed an used by the body. Finding a phyisian to write off-label
is sometimes hard because it is done on an individual basis and
without FDA approval. By putting themselves outside of FDA
Guidelines, they leave themselves at risk for a lawsuit if anything
goes wrong. I don't like it, but that's the way it is. Physicians
aren't comfortable writing for drugs without FDA approval and the
only way we will get FDA approval for rosacea is through controlled
clinical trials. And that would require those 'big, bad drug
companies' to spend millions of dollars on testing. If you really
believe in this as much as you seem to, I truly hope that you are
able to find a physician in research to run a small clinical trial.
If a small trial proves safe and effective, I assure you that the
drug companies will listen and be more than willing to pay for more
testing.
Angela
--- In rosacea-cure@yahoogroups.com, Dave Fleming <fulltruth40@y...>
wrote:
> Absolutely, and no doubt about it. The entire premise of the
existence of the (rosacea-cure @yahoogroups.com) I have been forced
to start, is that I am betting that there are even just a few doctors
who will care enough about their rosacea patient, to prescribe DMSO-
fluconazole, (named FLUCONAZOLE 1% SOLUTION), for rosacea. This med
has been proved harmless in over four years of being prescribed for
nail-fungus.
> If they care, they will dictate whatever controls and cautionary
testing, (e.g. for the extremely rare allergic reaction), they deem
necessary, and allow rosaceans at least a "controlled trial use" of
this effective treatment/cure for rosacea. If even a few doctors do
this, then over a hundred million rosaceans, worldwide, will easily
be able to get rid of their rosacea, as I have mine.
> All the facts are at:
> <http://groups.yahoo.com/group/rosacea-cure/>
> <http://groups.yahoo.com/group/rosacea-cure/message/2>
> <http://groups.yahoo.com/group/rosacea-cure/message/18>
> <http://groups.yahoo.com/group/rosacea-cure/message/64>
> God Bless,
> Dave Fleming
Here is another reply from Dave to Angela - message 159 click here.
> Jacy <jacy@a...> wrote:
> Absolutely. A stubborn, make me do it whether or not I wanted to
(and I didn't) doctor made me have the test that found cancer.
Without her, I wouldn't be here today. Thank God for good doctors.
> Hugs,
> Jacy
> ----- Original Message -----
> From: JyotiK2052@a...
> To: rosaceans@yahoogroups.com
> Sent: Thursday, June 19, 2003 11:36
> Subject: Re: [rosaceans] Integrity, in Medical Care?
>
>
> Jacy, I couldn't agree with you more. I come from a medical
background, and
> so know that there are 'bad' doctors as well as 'good' doctors.
Each person
> must be judged on their merits, and common sense must prevail.
I've known
> plenty of 'bad' docs, but I've known more 'good' ones. They are
the ones who will
> hang in there with you until you are either better or they can
say to you
> honestly: "I don't know what else to do...but I'll keep
researching for you..."
> - Jyoti
From: Dave Fleming <fulltruth40@y...>
Date: Fri Jun 20, 2003 8:15 pm
Subject: [FLUCONAZOLE 1% SOLUTION], and Integrity, in Medical Care?
Message # 133
ADVERTISEMENT
Hi, Angela,
Thank you for your interest in this most amazing treatment/cure for rosacea,
ever to exist.
First of all, this med is only applied topically, so it is intrinsically
extremely more difficult for it to cause problems, than if it were orally taken.
Also, the skin on the toes and/or fingers is in fact just as "sensitive" as the
skin of the face, and that is where this med has proven itself as extremely
harmless. No reports... Let's repeat that, Angela. There have been NO REPORTS
of any significant adverse effects or side effects, in over four years of being
prescribed for use on the SKIN around the finger nails and/or the toe nails,
(as well as on the nails).
As for the terminology of "off-label use", there is a grey area here, that you,
(and most people), are not aware of. This DMSO-fluconazole, (named FLUCONAZOLE
1% SOLUTION), can only be created by COMPOUNDING PHARMACISTS. This situation
is perhaps best explained, by referring you to the FDA Approval Statement, at:
<http://groups.yahoo.com/group/rosacea-cure/message/18>
This explains that a new "indication" for an already tested and "FDA approved"
med, is completely viable and acceptable to the FDA, although a new, costly,
and lengthy "clinical trial" is considered redundant and unnecessary.
The power, and decision to use any med for a "new indication", (i.e. a new use
for the med, which is not listed in the original FDA approval), is evidently
put in the hands of MDs.
You are right about our being in a lawsuit-prone "society".
(1) So perhaps the MD could suggest in this case, that the rosacea patient
would have to sign a waiver of liability document.
(2) Also, obviously, the MD would apply the med first, on a small area,
(perhaps on the inside of your arm), to test for the extremely rare allergic
reaction.
(3) Then, whatever other course would be followed, satisfying the MD that all
care was being taken, to avoid problems.
It sounds so easy to me. Since the stakes are so high, (i.e. curing over a
hundred million rosacea patients), it seems to me that any MD who cares for
their patient, would have to help them try this. This is not even including the
fact that the first MDs who establish this highly effective treatment/cure for
rosacea, will no doubt be seen as real heros, and even most likely receive
awards for their help in bringing this to every rosacea patient.
Otherwise, if this were to be put into the hands of the "clinical trial"
people, the "politics" of the situation would easily lead to this effective
treatment/cure for rosacea being intentionally "buried" and lost, and all the
profit of the next 50 or 100 years from "helping" rosaceans, would continue to
roll in.
You have assured me, that that will not happen, but I cannot even be sure that
you are not on the "mega-drug companies' payroll". I do not say this to insult
you, but to make you wonder why you are so sure you can assure me, "that the
drug companies will listen", as you put it. They stand to lose (trillions?,
quadrillions?) of dollars of future profit, if this DMSO-fluconazole, (named
FLUCONAZOLE 1% SOLUTION), is the silver bullet for rosacea that I believe it
is. When you cure all rosacea patients, (and also those rosacea patients not
yet born), you are talking about ending an "industry" that is more powerful
than most people can imagine.
With some considerable life experience, including years of work in the
pharmacological/medical research field, I say to you plainly, confidence is
extremely high that 100% of all rosacea will be ended by this med, because I
know/believe it is attacking the CAUSE of the rosacea. Nothing has ever been
known to do that before.
So, I have good news and bad news for you, Angela. The good news, is that
millions of dollars do NOT need to be spent, to make this med available to
treat/cure rosacea. The bad news, is that if enough rosaceans do not put
enough pressure on their MDs, and if enough MDs do not care enough to help
establish this treatment/cure, it will be lost, possibly permanently, in my
humble opinion.
Please join (rosacea-cure), Angela. Educate yourself competely, at:
<http://groups.yahoo.com/group/rosacea-cure/>
<http://groups.yahoo.com/group/rosacea-cure/message/2>
<http://groups.yahoo.com/group/rosacea-cure/message/18>
<http://groups.yahoo.com/group/rosacea-cure/message/64>
and help fight the good fight.
God Bless,
Dave Fleming
akbreshears <abreshears@h...> wrote:
Dave,
I have to tell you that I am extremely disturbed by some things you
are saying. Your claims that this is completely harmless is at the
very least misleading. Just because this was harmless to you means
nothing to the next person who tries it. You have no idea what kind
of allergic reactions or permenant scars this could lead to in other
people! This has only been tested for nail fungus. Nails are very
different from the sensitive tissue on our faces!
Now I'm not trying to discount your claim that this worked for you
and I'm sure that you have nothing but the best intentions with this,
but if anyone is going to try this they should know that they are
putting themselves at risk. Then, if they are willing to take that
risk- Go for it! I'm considering trying this if my doctor will write
for it, but it will be in a very small area long before I would ever
use it in an obvious area.
Also, do you know what the term "off-label use" means? If not you
should look into that. What you are asking for is "off-label use"
not "controlled-trial use" as you've said before. These are two very
different things! Controlled-trials are full of additional safety
precautions and lab work to watch exactly how the drug is being
absorbed an used by the body. Finding a phyisian to write off-label
is sometimes hard because it is done on an individual basis and
without FDA approval. By putting themselves outside of FDA
Guidelines, they leave themselves at risk for a lawsuit if anything
goes wrong. I don't like it, but that's the way it is. Physicians
aren't comfortable writing for drugs without FDA approval and the
only way we will get FDA approval for rosacea is through controlled
clinical trials. And that would require those 'big, bad drug
companies' to spend millions of dollars on testing. If you really
believe in this as much as you seem to, I truly hope that you are
able to find a physician in research to run a small clinical trial.
If a small trial proves safe and effective, I assure you that the
drug companies will listen and be more than willing to pay for more
testing.
Angela
--- In rosacea-cure@yahoogroups.com, Dave Fleming <fulltruth40@y...>
wrote:
> Absolutely, and no doubt about it. The entire premise of the
existence of the (rosacea-cure @yahoogroups.com) I have been forced
to start, is that I am betting that there are even just a few doctors
who will care enough about their rosacea patient, to prescribe DMSO-
fluconazole, (named FLUCONAZOLE 1% SOLUTION), for rosacea. This med
has been proved harmless in over four years of being prescribed for
nail-fungus.
> If they care, they will dictate whatever controls and cautionary
testing, (e.g. for the extremely rare allergic reaction), they deem
necessary, and allow rosaceans at least a "controlled trial use" of
this effective treatment/cure for rosacea. If even a few doctors do
this, then over a hundred million rosaceans, worldwide, will easily
be able to get rid of their rosacea, as I have mine.
> All the facts are at:
> <http://groups.yahoo.com/group/rosacea-cure/>
> <http://groups.yahoo.com/group/rosacea-cure/message/2>
> <http://groups.yahoo.com/group/rosacea-cure/message/18>
> <http://groups.yahoo.com/group/rosacea-cure/message/64>
> God Bless,
> Dave Fleming
> Jacy <jacy@a...> wrote:
> Absolutely. A stubborn, make me do it whether or not I wanted to
(and I didn't) doctor made me have the test that found cancer.
Without her, I wouldn't be here today. Thank God for good doctors.
> Hugs,
> Jacy
>
> ----- Original Message -----
> From: JyotiK2052@a...
> To: rosaceans@yahoogroups.com
> Sent: Thursday, June 19, 2003 11:36
> Subject: Re: [rosaceans] Integrity, in Medical Care?
> Jacy, I couldn't agree with you more. I come from a medical
background, and
> so know that there are 'bad' doctors as well as 'good' doctors.
Each person
> must be judged on their merits, and common sense must prevail.
I've known
> plenty of 'bad' docs, but I've known more 'good' ones. They are
the ones who will
> hang in there with you until you are either better or they can
say to you
> honestly: "I don't know what else to do...but I'll keep
researching for you..."
> - Jyoti
Here is another email to read on this >
http://groups.yahoo.com/group/rosacea-support/message/53940
If you still want more information, here is more:
Fluconazole • Dave's Directions • DMSO Fluconazole Formula • CP Locator
