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DIRECTIONS FOR THE USE OF [DMSO + FLUCONAZOLE], TO TREAT ROSACEA
[The below directions must be approved by the attending doctor,
to be acceptable and valid.]
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ADVISORY DISCLAIMER by Dave Fleming:
The following directions are as simple as I have been able to make them. Of course, these Directions must be approved by the attending doctor, to be acceptable and valid. However, I would stake my life on the accuracy and appropriateness of these directions for treating/curing rosacea with
[DMSO + FLUCONAZOLE], whether it is [FLUCONAZOLE 1% SOLUTION], or the more effective, convenient, and economical [FLUCONAZOLE 10% SOLUTION].
(Step 1) If possible, obtain the new, much more efficient
[DMSO + 10% FLUCONAZOLE] SOLUTION prescription. If necessary, use the
[DMSO + 1% FLUCONAZOLE] SOLUTION, until you can convince your doctor
to give you a prescription for the [FLUCONAZOLE 10% SOLUTION].
These prescriptions are currently, (i.e. May 7, 2004), available from
Michael Roberge, RPh, and Compounding Specialist, at:
compoundedsolutions.com
at the following prices:
[FLUCONAZOLE 1% SOLUTION] is $47.00 per 15 milliliters.
[FLUCONAZOLE 10% SOLUTION] is $102.00 per 15 milliliters, making it much more economical and cost-effective, with five times the fluconazole for the same cost.
Although these topically applied prescriptions are benign, and have virtually no effect on healthy skin, they have substantial effects on rosaceous skin, and some of these effects are delayed, by many days. Although these effects are not medically serious, the psychological effects of temporary increased redness, wrinkling, and peeling of the facial skin, can be very uncomfortable.
Therefore, each individual must decide how many applications of this medication to apply, depending on the over-all temporary psychological effects this treatment might cause, in each individual's unique circumstances. The final result of this treatment will be the total eradication of the "rosacea causing entity", no matter what rate of progress of the treatment may be decided by the patient.
The rate of progress of this treatment is not as important as is the maintaining of the psychological comfort zone of each individual rosacea patient, in their everyday life, as this treatment proceeds.
It should also be understood, that the damage that may have been done by the rosacea, such as some minor visible purple veins in my case, will not be removed by this treatment. Even though these small veins still show on the left side of my nose, my facial skin has been completely healthy for over 22 months after I experienced this treatment/cure, from about Nov. 2001 through June 2002.
(Step 2) With the above facts in mind, (using either a q-tip, or the applicator brush supplied), make only (1) one light, full-face application of the liquid medication to all parts of the face, making certain, that no medication comes into contact with the eyeball or eye socket.
Note carefully, where the stinging "reaction" occurs, and any changes in appearance of the facial skin. Take care, to not drop or tip over the small bottle of medication, since this is expensive and easy to spill.
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CAUTIONARY NOTE: Be CERTAIN, to carefully read and apply the directions given, at:
http://groups.yahoo.com/group/rosacea-cure/message/189
http://groups.yahoo.com/group/rosacea-cure/message/190
These directions state that no other substance should be present, when this medication is being applied or absorbed into the skin. The DMSO, (i.e. Dimethyl Sulfoxide), content of this medication has the ability to carry almost any substance into the skin. Although this might not be dangerous, unless a toxic substance such as a pesticide were present, it might possibly cause unwanted effects.
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A very small percentage of this medication is absorbed into the bloodstream, and even ocular rosacea has been successfully treated, by ONLY applying this medication to the SKIN of the face. It MIGHT be dangerous, to apply this medication to the eyeball directly. Therefore USE EXTREME CAUTION, and do NOT allow this medication to come into any direct contact with the eyeballs, or with the eye sockets.
(Step 3) Also, at the same time as (Step 2), but in a reclining position, with the head back, use two q-tips dipped in medication, one to treat each nostril, inside the nose, as far back as a q-tip can reach. Maintain the reclining position, for at least ten minutes. After use, do not re-dip the q-tip in the medication.
Note carefully, if there is any stinging, inside the nose. If stinging occurs, be sure to repeat treating the inside of the nose, as in (Step 6), (Step 7), and (Step 8). Swallow any medication that runs back into the throat, from the nose.
If the cartilage inside the nose is infested, this may prove to require the longest treatment, since cartilage has almost no blood supply, and this infestation may therefore be much more resistant to this treatment. I have found the [FLUCONAZOLE 10% SOLUTION] to be much more effective, against the infestation inside my nose, which may or may not be connected to rosacea.
(Step 4) OPTIONAL: If the attending physician agrees, it should be very beneficial to treat the inside of the cheeks, at the same time as (Step 2) and (Step 3), by applying several q-tips of medication to that area, inside the mouth.
Or, less than (5) five milliliters of the [FLUCONAZOLE 1% SOLUTION], or
less than (1) one milliliter of the [FLUCONAZOLE 10% SOLUTION] could be swished around in the mouth for an extended time period of ten minutes or more. This medication can then either be swallowed, for its whole body effect(s), (which might benefit ocular rosacea more), or it can be spit out.
If the medication is to be swallowed, it would most likely be better to be conservative, and NOT perform (Step 4) more than once every one or two months.
(Step 5) Observe and assess the effects of these applications, as in (Step 2), (Step 3), and (Step 4), for one week, without further applications of the medication. If necessary, use an antibiotic ointment on the skin to prevent any possible infection.
Do NOT aggressively rub off all the unsightly peeling skin. If possible, use the anti-inflammatory, anti-wrinkle face cream recommended, at:
http://groups.yahoo.com/group/rosacea-cure/message/204
to blend in the peeling skin, so that it does not show during the day, as well as at night, to sooth the skin. The name of this cream is:
----Reviva Labs: Alpha-Lipoic-Acid-Vitamin-C-Ester-&-DMAE Cream----
The use of some sort of non-irritating "Concealer", or "cover-up makeup" is advisable, to maintain a normal appearance and schedule. Since some characteristic "healing itch" may occur, as healthy skin grows during the waiting periods, it may be difficult to perfectly maintain this "cover-up makeup".
If possible, study the book, "The Perricone Prescription", by Dr. Perricone, and use the anti-inflammation supplements and diet he advises, (NOT for the "Weight Loss" schedule). The book, supplements, and face cream are available inexpensively from the Vitamin Shoppe stores, at vitaminshoppe.com, or through their toll-free phone number, at 1-800-223-1216.
Although the cream, book, supplements, and diet are NOT necessary, they should enhance the patient's immune system, and facilitate the growth of new skin, which is an essential part of this treatment.
(Step 6) Based on the patient's individual assessment, of the effects of the application(s) of this medication, each individual patient must decide the rate of progress of this treatment. Whether only one application is made, or multiple applications are made, (at one time), and how long the waiting period will be, between applications, is to be decided by the patient, to comfortably fit this treatment into their individual schedule as well as possible, and maintain as much psychological well-being as possible.
I would like to emphasize, as my personal opinion, that continuous daily application(s) of this medication probably do NOT speed up this treatment/cure, and MAY simply cause UNNECESSARY SUFFERING for the patient, and waste medication. The immune system requires weeks, to effectively "clear away" the destroyed "rosacea causing entity", (allowing the growth of new, healthy skin), after each "cycle", of application of medication. Therefore, the method in (Step 7) is most likely the best way of applying this medication.
(Step 7) As the overall methodology of treatment, it is recommended that a heavy, multiple application of the medication be applied to the full face, [or only to the parts of the face that "react", as in (Step 2), by stinging], waiting about ten minutes, for each application to be absorbed into the skin. Then, a substantial waiting period without applications should be allowed,
of FROM ONE TO FOUR WEEKS,
for new, healthy skin to grow back, replacing the rosaceous skin that has been affected by the treatment.
During the waiting periods, some feverishness and redness of the immune system's functioning may be noticed, in the skin. This is to be expected, since the immune system may be removing the "rosacea causing entity", which the immune system may not have been able to remove, during decades of past growth of this "rosacea causing entity" in the skin.
Although this theory of mechanism has not been proven yet, no proof is necessary, for repeated "cycles" of treatment to finally effect the 100% eradication of this stealthy, apparently parasitical "rosacea causing entity", even though this may take many months, to accomplish 100%.
(Step 8) If significant stinging occurs, and/or any pattern of infestation appears on the skin, when this medication is applied, then this treatment should NOT be discontinued. Repeat (Step 5), (Step 6), and (Step 7), until there is little or no stinging, and no subsequent redness or peeling of skin, after the medication is applied.
(Step 9) A major drawback of this treatment to cure rosacea, is that the discomfort of temporary stinging, redness, wrinkling, and skin peeling, combined with the initial improvement of the rosacea symptoms, may convince the patient to discontinue applications of this medication too soon.
The med application and waiting period "cycles" should be continued, until this treatment is complete, as defined in (Step 8).
If the patient stops this treatment just because rosacea symptoms have disappeared, then the rosacea symptoms are guaranteed to return later, because the "rosacea causing entity" has not been completely eradicated.
Although this assertion has not been proven, by the many years of double blind Clinical Studies that would prove it, it is only reasonable and logical that this assertion is accurate, and will be proven by the experience of each patient.
(Step 10) After eradicating the "rosacea causing entity", it may be that in coming years the stealthy, unseen "rosacea causing entity" might return, (which is NOT a remission and return), without initially causing any rosacea symptoms. Therefore, it is recommended that this medication be applied once a year, or once every five years, (at the patient's discretion), even though no rosacea symptoms may be present.
If stinging occurs, continue to repeat (Step 5) through (Step 8), until little or no stinging occurs, and no subsequent redness and peeling skin occur.
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END OF DIRECTIONS FOR THE USE OF [DMSO + FLUCONAZOLE], TO TREAT ROSACEA
[The above Directions must be approved by the attending doctor,
to be acceptable and valid.]
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If you have any questions about these directions email Dave.
