Ivermectin (Stromectol)

Ivermectin (Stromectol) is a drug used in the USA for the eradication of mites in animals. It was announced at a yahoo r-s group on October 20, 2004 that this drug may give significant relief to some rosaceans. Here is a quote,

"... Oral Ivermectin (Stromectol) is making a huge difference in these sufferers facial symptoms and flushing triggers (yes, I said flushing triggers). Ivermectin is an anti-mite drug that is related to the macrolide antibiotics. It has a very good safety profile and less side effects than most antibiotics (and not one major side effect)..." source

This announcement has raised a number of questions and comments at the r-s yahoo group. I try to keep up with anything new that can help rosaceans so that is why this article is posted on my site.

The Management of Rosacea. By: Rebora, A., American Journal of Clinical Dermatology, states, "...Oral or topical ivermectin may also be useful in such cases..." source

With little concern that the drug may have some unknown side effects, time will tell and no doubt many will report not only if their rosacea clears up but also the immediate side effects or future side effects which may show up years from now. We shall no doubt find out soon if rosaceans report significant clearing of their rosacea since many rosaceans may try this drug. There are always risks and side effects with taking any prescription drug. You, as a rosacean, have to decide if you are willing to except these risks and side effects if the benefits are worth it. The rosacea pioneers go where no one has gone before.

One should remember that this prescription drug has few, if any, clinical trial research studies for rosacea and some have already reported one of the side effects is upset stomach. More reports will come forth without a doubt. The long term effects are not known. I would recommend the Z cream since it is a lot safer and works.

So far the first report of a rosacean trying Ivermectin can be read by clicking here. This user began using Ivermectin sometime before July 12, 2004 and is continuing to use it. Another user. And now there are reports of others who are trying this drug. One report says there is a Ivermectin Cream? Now that sounds better, but I am sure the Z cream would be safer.

For more information on Ivermectin click here. And this message. Here is a positive experience. Interesting Clinical Studies - drug.com report -

One clinical study in Germany says Ivermectin was ineffective and oral metronidazole was better! [source] Who can figure any of this out? Dr. Nase says oral metronidazole has no effect on demodex. [source] His comment on the clinical study in Germany.

Warning.

Here are more reports of using Ivermectin:

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Buy Stromectol [Ivermectin]

You may want to participate in a clinical study taking Ivermectin if you are a rosacean. Check this out

[Demodecidosis in a patient infected by HIV: successful treatment with ivermectin]
Clyti E, Sayavong K, Chanthavisouk K.

Service de Dermatologie, Institut Guyanais de Dermatologie Tropicale, Hopital de Cayenne, Guyane Francaise.

INTRODUCTION: Demodex is a saprophyte parasite in mammals. In Man, it is associated with differing clinical profiles (rosacea-like dermatitis, folliculitis and blepharitis). We report a case of demodecidosis in an HIV-infected patient that was successfully treated with ivermectin. CASE REPORT: A man from Laos, infected by HIV and treated for glandular tuberculosis, presented with a prurigenous eruption on the face and the pre-sternal and interscapular areas. Direct examination of scraped product and histopathological examinations confirmed the diagnosis of demodecidosis. Clinical cure was obtained after 2 single cures of ivermectin a one month's distance. DISCUSSION: The features of demodecidosis are often similar to those of rosacea. In immunodeficient patients, the semiology remains the same but the eruption is more abundant. During HIV-infection, demodecidosis occurs at the AIDS stage or with a CD4 count lower than 200/mm3. Many anti-dust mite molecules are used to treat the disease but frequently lead to irritation. Administration of a single cure of ivermectin, repeated if necessary, appears to be an interesting alternative to contact anti-dust mite agents. source